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Entacapone

Product Name Entacapone
Price (USD) *Get Latest Price
CAS Number 130929-57-6
Synonyms 2-cyano-3-(5-dihydroxyamino-3,4-dioxo-1-cyclohexa-1,5-dienyl)-n,n-diethyl-prop-2-enamide
Molecular Formula C14H15N3O5
Molecular Weight 305.286 (g/mol)
characteristics Yellow crystalline solid

Entacapone

 

Detail Description about this product

Packaging

25 kg per Barrel
Less than 10 kg Use Bagged
(Or According to your requirement)

Description

Entacapone is a drug that functions as a catechol-O-methyl transferase (COMT) inhibitor. It is used in the treatment of Parkinson's disease.Entacapone is a member of the class of drugs known as nitrocatechols.

Pharmacologically, entacapone is somewhat similar to carbidopa or benserazide, in that it is an inhibitor of an enzyme that converts L-DOPA into a compound that cannot cross the blood brain barrier. Carbidopa and benserazide inhibit aromatic L-amino acid decarboxylase, which converts L-DOPA into dopamine, which cannot cross the blood brain barrier.

When administered in conjunction with dopaminergic agents such as L-DOPA, entacapone prevents COMT from metabolizing L-DOPA into 3-methoxy-4-hydroxy-L-phenylalanine (3-OMD) in the periphery, which does not easily cross the blood brain barrier (BBB).

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